The Marathon de La Rochelle is an annual road running event which takes place in late November in La Rochelle, France. It features a full 42.195 km marathon race as well a 10 km race for amateur runners, a half marathon for wheelchair athletes, and a recreational 4 km jog around the city’s harbour.

The city of La Rochelle had its first marathon race in 1981. This competition lasted until 1989 (with shorter 20 km races occurring in 1983 to 1985). Following the absence of a race in 1990, the Marathon de La Rochelle was established in its place, having its first edition on 24 November 1991. The marathon is one of the most popular in France, having had a record high of 10,000 entrants and 8625 finishers at the 20th edition in 2010.

Among French races, only the Paris Marathon has had greater participation. Following the sudden death of Serge Vigot, the race founder and president of the organising committee, during the 2005 Marrakech Marathon, the event was officially renamed the Marathon De La Rochelle – Serge Vigot in his honour. The race as awarded IAAF Bronze Label Road Race status for the first time in 2011.