The Cross Internacional de Itálica is an annual cross country running competition it will be held on 21st of November in Santiponce, near Seville, Spain. Inaugurated in 1982, the race course is set in the ruins of the ancient Roman city of Italica. As one of only two Spanish competitions to hold IAAF permit meeting status, it is one of the more prestigious races on the Spanish cross country circuit.

The competition comprises three general categories of race: children's and junior races, the mass participation ("popular") race, and the professional international races. The men's international race was a 10km race until 1999 when it was increased to roughly 11km. The distance of the women's international race (currently 8km) has also fluctuated, varying between 5.5km and 6.6km in its early years.The course of the race loops through the ancient streets of Itálica, passing alongside ruins throughout.The red clay ground usually makes for a dry running surface, although rain has occasionally made this a particularly difficult, muddy course in previous editions.